Endocrine Abstracts

The pathophysiology of type 2 DM is complex and involves insulin resistance, pancreatic beta cell dysfunction and visceral adiposity. The levels of free fatty acids (FFA) increases in obese persons and diabetic patients. Elevated levels of FFAs may cause resistance and deficient insulin secretion. Our aim in this study was to investigate the change of FFA levels, glucose, insulin and triglyceride in fasting and postprandial state in 15 healthy controls and 45 diabetic patients...

ACTH-independent micronodular adrenocortical hyperplasia is a rare cause of Cushing syndrome. In some forms of micronodular adrenal disease, darkly pigmented micronodules are seen in the presence of atrophy of the peripheral adrenal tissue. In most cases of pigmented micronodular hyperplasia Carney complex is associated with the disease. Here, we present a case of Cushing syndrome due to sporadic primary pigmented micronodular hyperplasia not accompanied by Carney complex....

Both hyperhomocysteinemia and increased inflammatory activity are shown to be associated with atherosclerosis. But, the relation of inflammatory activity to homocysteine levels is not well established. In the present study, we aimed to evaluate the relation of plasma homocysteine (tHcy) levels to atherosclerotic vascular disease and inflammatory activity in type 2 diabetic patients.Ninty type 2 diabetic patients were included in the study. Forty one of t...